The use of insect cell lines as production hosts is an emerging technology for the production of bio pharmaceuticals. There are currently more than 100 insect cell lines available for recombinant protein production with lines derived from ''

Bombyx mori The domestic silk moth (''Bombyx mori''), is an insect from the moth family Bombycidae. It is the closest relative of ''Bombyx mandarina'', the wild silk moth. The silkworm is the larva or caterpillar of a silk moth. It is an economically imp ...

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Mamestra brassicae The cabbage moth (''Mamestra brassicae'') is primarily known as a pest that is responsible for severe crop damage of a wide variety of plant species. The common name, cabbage moth, is a misnomer as the species feeds on many fruits, vegetables, ...

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Spodoptera frugiperda The fall armyworm (''Spodoptera frugiperda'') is a species in the order Lepidoptera and one of the species of the fall armyworm moths distinguished by their larval life stage. The term "armyworm" can refer to several species, often describing the ...

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Trichoplusia ni The cabbage looper (''Trichoplusia ni'') is a medium-sized moth in the family Noctuidae, a family commonly referred to as owlet moths. Its common name comes from its preferred host plants and distinctive crawling behavior. Cruciferous vegetab ...

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Drosophila melanogaster ''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Ch ...

'' being of particular interest. Insects cell lines are commonly used in place of

prokaryotic A prokaryote () is a Unicellular organism, single-celled organism that lacks a cell nucleus, nucleus and other membrane-bound organelles. The word ''prokaryote'' comes from the Greek language, Greek wikt:πρό#Ancient Greek, πρό (, 'before') a ...

ones because post-translational modifications of proteins are possible in insect cells whereas this mechanism is not present in prokaryotic systems. The

Sf9 SF9 ( ko, 에스에프나인 ; shortened from Sensational Feeling 9) is a South Korean boy band formed by FNC Entertainment and the company's first dance boy group. Consisting of nine members, the group debuted on October 5, 2016 with the relea ...

cell line is one of the most commonly used lines in insect cell culture.

References and notes

Cell culture techniques Biopharmaceuticals {{Pharmacy-stub